3-[(2-Aminoethyl)dithio]propionic acid

CAS: 15579-00-7

Ref. 3D-FA17745

Product Information

• Name: 3-[(2-Aminoethyl)dithio]propionic acid
• Brand: Biosynth
• Description: Dithiobis(3-mercaptopropionate) is an analog of 3-[(2-Aminoethyl)dithio]propionic acid (DTA). It has been used as a cross-linking agent for the synthesis of polymers with acidic pH. Dithiobis(3-mercaptopropionate) is also used for the synthesis of conjugates and bifunctional molecules. Dithiobis(3-mercaptopropionate) can be synthesized by reacting bis(sulfanylmethyl)amine with sodium azide in an acidic solution. The cross-linking reaction will produce a disulfide bond, which is a covalent linkage between two cysteine residues in two different polypeptides or proteins. This crosslink is irreversible, so it cannot be broken down by chemical processes, but can be broken down by enzymatic digestion.

Chemical properties

• Molecular weight: 181.28 g/mol
• Formula: C₅H₁₁NO₂S₂
• Purity: (%) Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H11NO2S2/c6-2-4-10-9-3-1-5(7)8/h1-4,6H2,(H,7,8)
• InChI key: InChIKey=HMMFDEBVQNRZLJ-UHFFFAOYSA-N
• SMILES: NCCSSCCC(=O)O