Product Information
- 6-Isopropoxy-9-oxoxanthene-2-carboxylic acid
- 6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid
- 9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo-
AH 6809 is an antagonist of the prostaglandin 2 (PGE2) receptor, which is a member of the G protein-coupled receptor superfamily. It has been shown to inhibit PGE2 release in human colon cells and mouse models of colitis. AH 6809 inhibits the expression of IL-6, IL-8, and TNF-α in human monocytes stimulated with lipopolysaccharide (LPS). This drug also decreases activation of NF-κB, a transcription factor that regulates inflammatory responses. The mechanism by which AH 6809 works is not yet understood.
Chemical properties
Technical inquiry about: 3D-FA177523 AH 6809
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