N-(5-Aminopentyl) methotrexate amide

CAS: 136672-64-5

Ref. 3D-FA17806

Product Information

• Name: N-(5-Aminopentyl) methotrexate amide
• Synonyms: N-(5-Aminopentyl)-N2-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamineMTX-DAP
• Brand: Biosynth
• Description: N-(5-Aminopentyl) methotrexate amide is a fluorescent probe that is used to study the transport of drugs across cell membranes. It binds to the plasma membrane of cells and can be visualized with a fluorescence microscope. N-(5-Aminopentyl) methotrexate amide has been shown to bind to leukemia cells in murine leukemia models. It has a high affinity for drug-resistant cells, which makes it useful for studying drug resistance mechanisms. This probe can be used at nanomolar concentrations for imaging studies, as well as for measuring the uptake of drugs into cancer cells by flow cytometry.

Chemical properties

• Molecular weight: 538.6 g/mol
• Formula: C₂₅H₃₄N₁₀O₄
• Purity: Min. 95%
• Color/Form: Yellow Powder