[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide

CAS: 284462-37-9

Ref. 3D-FA17813

Product Information

• Name: [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide
• Synonyms: 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide4-(4-Aminophenoxy)-N-methylpicolinamide4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]an iline, 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl-, 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide, 4-(4-Aminophenoxy)-N-methylpicolin Amide, 4-(4-Aminophenoxy)pyridine-2-carboxylic acid methylamide, 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide, 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline, 4-[[2-(Methylcarbamoyl)pyridin-4-yl]oxy]aniline, 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]aniline, 4-[[2-(N-Methylcarbamoyl)pyridin-4-yl]oxy]aniline, N-Methyl-4-(4-aminophenoxy)pyridine-2-carboxamide, [4-(4-Aminophenoxy)(2-Pyridyl)]-N-Methylcarboxamide

Description

4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide is a chemical compound that inhibits the growth of cancer cells by binding to the active site of b-raf and blocking its activity. It has been shown in a pharmacokinetics study that 4-(4-aminophenoxy)(2-pyridyl)]-N-methylcarboxamide is absorbed rapidly through the oral administration, excreted in urine, and eliminated rapidly from the body. The optimal reaction for this drug was found to be at pH 7.0 with an ionic strength of 0.1 M (sodium chloride). This drug also has significant inhibitory activities against human cervical carcinoma and breast cancer cell lines (MDA-MB-231).

• Brand: Biosynth

Chemical properties

• Molecular weight: 243.26 g/mol
• Formula: C₁₃H₁₃N₃O₂
• Purity: Min. 95%
• Color/Form: Off-White To Beige To Light Brown Solid
• InChI: InChI=1S/C13H13N3O2/c1-15-13(17)12-8-11(6-7-16-12)18-10-4-2-9(14)3-5-10/h2-8H,14H2,1H3,(H,15,17)
• InChI key: InChIKey=RXZZBPYPZLAEFC-UHFFFAOYSA-N
• SMILES: CNC(=O)c1cc(Oc2ccc(N)cc2)ccn1