Amitriptyline N-oxide

CAS: 4317-14-0

Ref. 3D-FA178736

Product Information

• Name: Amitriptyline N-oxide
• Synonyms: 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-N-oxide, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine N-oxide, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta5,gamma-propylamine-N-oxide, 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin N-oxid, 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-N-oxide, 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-, N-oxide, Ambivalon, Amioxid, Amitriptilinoxido, Amitriptilinoxido [INN-Spanish], Amitriptyline oxide, Amitriptylinoxide [INN], Amitriptylinoxidum, Amitriptylinoxidum [INN-Latin], Amitriptylinoxyde, Amitriptylinoxyde [INN-French], Brn 2385442, Equilibrin, Unii-Tyr2U59Wma, [3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl]dimethylamine oxide

Description

Amitriptyline N-oxide is an amine that is metabolized in the liver by cytochrome P450 and N-oxidases. It has been shown to inhibit the uptake of a number of drugs, including imatinib, and inhibit their oxidation by cytochrome p450. Amitriptyline N-oxide has also been shown to affect blood pressure in humans. The compound class of amitriptyline N-oxide includes a number of other drugs, such as octopamine, tyramine, dopamine, ephedrine and amphetamine. Amitriptyline N-oxide is oxidized to amitriptyline by human liver microsomes and can be used as a biochemical probe for compounds with similar structures. The profile of amitriptyline N-oxide can be used to identify other compounds with similar structures.

• Brand: Biosynth

Chemical properties

• Molecular weight: 293.4 g/mol
• Formula: C₂₀H₂₃NO
• Purity: Min. 95%