Amtolmetin guacil

CAS: 87344-06-7

Ref. 3D-FA17894

Product Information

• Name: Amtolmetin guacil
• Synonyms: N-[2-[1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]glycine 2-methoxyphenyl esterAmtolmethin guacilAmtolmetin guacyl, (2-Methoxyphenyl)2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino]acetate, 2-Methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetamido)acetate, 2-Methoxyphenyl N-{[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl}glycinate, 87344-06-7, Amtolmethin guacil, Amtolmetin guacyl, Finrid TM, Glycine, N-[2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]-, 2-methoxyphenyl ester, Glycine, N-[[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]-, 2-methoxyphenyl ester, Med 15, St 679

Description

Amtolmetin guacil is a nonsteroidal anti-inflammatory drug that belongs to the group of gsh-px activities. It is used to treat pain and inflammation in patients with inflammatory diseases. Amtolmetin guacil has shown efficacy in treatment trials for rheumatoid arthritis, osteoarthritis, and other inflammatory diseases. Amtolmetin guacil inhibits the activity of P-glycoprotein (Pgp), which is an important protein that transports drugs out of cells, thus increasing its bioavailability. Amtolmetin guacil also has low bioavailability due to its fast metabolism by liver enzymes and rapid excretion by the kidney. This drug can be administered as a nanoparticulate composition to increase its absorption into cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 420.46 g/mol
• Formula: C₂₄H₂₄N₂O₅
• Purity: Min. 95%
• InChI: InChI=1S/C24H24N2O5/c1-16-8-10-17(11-9-16)24(29)19-13-12-18(26(19)2)14-22(27)25-15-23(28)31-21-7-5-4-6-20(21)30-3/h4-13H,14-15H2,1-3H3,(H,25,27)
• InChI key: InChIKey=CWJNMKKMGIAGDK-UHFFFAOYSA-N
• SMILES: COc1ccccc1OC(=O)CNC(=O)Cc1ccc(C(=O)c2ccc(C)cc2)n1C