Anthralin

CAS: 1143-38-0

Ref. 3D-FA17945

Product Information

• Name: Anthralin
• Synonyms: 1,8-Dihydroxyanthrone Dithranol, 1,8-Dihydroxy-10H-anthracen-9-one, 1,8-Dihydroxy-9,10-dihydroanthracen-9-one, 1,8-Dihydroxy-9-Anthrone, 1,8-Dihydroxy-Anthrone, 1,8-Dihydroxyanthracen-9(10H)-on, 1,8-Dihydroxyanthrone, 1,8-dihidroxiantracen-9(10H)-ona, 1,8-dihydroxy-9(10H)-anthracenone, 1,8-dihydroxyanthracen-9(10H)-one, 1,8-dihydroxyanthracene-9(10H)-one, 9(10H)-Anthracenone, 1,8-dihydroxy-, Anthra-Derm, Anthracene-1,8,9-Triol, Anthrone, 1,8-dihydroxy-, Batidrol, Batridol, Batridrol, Chrysodermol, Cignolin, Cigthranol, Cygnolin, Dermaline, Derobin, DithraSal, Dithrocream, DrithoCreme, Drithoscalp, Lasan, Nsc 43970, Nsc 629313, Psodadrate, Psoriacid-Stift, Psoriacide, Psorin
• CAS: 1143-38-0

Description

Anthralin is a synthetic retinoid that has been used to treat bowel diseases such as ulcerative colitis and Crohn's disease. Anthralin belongs to a class of drugs called "reactive" or "synthetic" retinoids, which are chemically similar to the natural form of vitamin A. It is thought that anthralin may work by altering the permeability of the cell membrane, which leads to an increase in reactive oxygen species and a decrease in mitochondrial membrane potential. In vivo studies on humans have shown that it can be used as a treatment for mild-to-moderate disease activity in ulcerative colitis, but not Crohn's disease. Anthralin has also been found to be effective at reducing the side effects of corticosteroids when used with them in combination therapy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 226.23 g/mol
• Formula: C₁₄H₁₀O₃
• Purity: Min. 95 Area-%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
• InChI key: InChIKey=NUZWLKWWNNJHPT-UHFFFAOYSA-N
• SMILES: O=C1c2c(O)cccc2Cc2cccc(O)c21