5-Azauracil

CAS: 71-33-0

Ref. 3D-FA18066

Product Information

• Name: 5-Azauracil
• Synonyms: s-Triazine-2,4-(1H,3H)-dioneAllantoxaidine, 1,2,3,4-Tetrahydro-1,3,5-triazine-2,4-dione, 1,3,5-Triazine-2,4-diol, 1H-[1,3,5]Triazine-2,4-dione, Allantoxaidin, Allantoxaidine, Ccris 3442, Nsc 56901, Oxaidin, s-Triazine-2,4(1H,3H)-dione, s-Triazine-2,4(1H,3H)-dione (8CI), s-Triazine-2,4-diol

Description

5-Azauracil is a glycosylase that specifically hydrolyzes the N-glycosidic bond in uridine. It is a potential anticancer agent that inhibits the growth of cancer cells by targeting intracellular targets and inhibiting enzyme activities. 5-Azauracil binds to nitrogen atoms in the enzyme active site, causing an alteration in the hydrogen bonding network and resulting in inhibition of enzyme activity. The reaction mechanism involves the formation of orotic acid as a product. 5-Azauracil also has been shown to inhibit x-ray diffraction data, which may be due to its ability to bind to an enzyme's metal cofactors such as iron or copper.

• Brand: Biosynth

Chemical properties

• Molecular weight: 113.07 g/mol
• Formula: C₃H₃N₃O₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C3H3N3O2/c7-2-4-1-5-3(8)6-2/h1H,(H2,4,5,6,7,8)
• InChI key: InChIKey=GEWRKGDRYZIFNP-UHFFFAOYSA-N
• SMILES: O=c1nc[nH]c(=O)[nH]1