3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide

CAS: 494772-86-0

Ref. 3D-FA18119

Product Information

• Name: 3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide
• Synonyms: AZ-TAK1 inhibitor3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide

Description

3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide is a chemical inhibitor that inhibits the activity of kinases. It has been shown to be cytotoxic against cancer cells and to induce apoptosis through a number of different mechanisms. 3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide binds to DNA and induces DNA repair, which can lead to cell death. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit pro-inflammatory cytokines such as TNFα and IL1β.

• Brand: Biosynth

Chemical properties

• Molecular weight: 360.43 g/mol
• Formula: C₁₇H₂₀N₄O₃S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C17H20N4O3S/c18-16(22)15-13(20-17(19)23)9-14(25-15)12-3-1-11(2-4-12)10-21-5-7-24-8-6-21/h1-4,9H,5-8,10H2,(H2,18,22)(H3,19,20,23)
• InChI key: InChIKey=MOWJKFWTFZWXHW-UHFFFAOYSA-N
• SMILES: NC(=O)Nc1cc(-c2ccc(CN3CCOCC3)cc2)sc1C(N)=O