Product Information
Name:Apremilast
Synonyms:
- (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
Brand:Biosynth
Description:Apremilast is the commercial name of a phosphodiesterase4 (PDE4) inhibitor developed to treat chronic inflammatory disorders. Similarly to thalidomide, the apremilast molecule carries a phthalimide ring, but it lacks however the glutarimide ring needed to bind to cereblon, specifically targeted by thalidomide. As a drug, apremilast is indicated for the treatment of psoriasis and psoriatic arthritis.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:460.5 g/mol
Formula:C22H24N2O7S
Purity:Min. 98 Area-%
Color/Form:White Powder
InChI:InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChI key:InChIKey=IMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILES:CCOc1cc([C@@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC
Technical inquiry about: Apremilast
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