(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid

CAS: 75028-24-9

Ref. 3D-FA33064

Product Information

• Name: (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid
• Synonyms: (Z)-5-Amino-alpha-(ethoxyimino)-1,2,4-thiadiazole-3-acetic acid, (αZ)-5-Amino-α-(ethoxyimino)-1,2,4-thiadiazole-3-acetic acid, 1,2,4-Thiadiazole-3-acetic acid, 5-amino-α-(ethoxyimino)-, (Z)-, 1,2,4-Thiadiazole-3-acetic acid, 5-amino-α-(ethoxyimino)-, (αZ)-, Atde, Ceftazidime Norlin Intermediates

Description

(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid is a synthetic compound that can be used as an antibiotic. It is synthesized from acetonitrile and phosphorus oxychloride in the presence of hydroxyl groups. This reaction yields a mixture of amides and cyanoacetamide derivatives. The amides are then converted to their respective alkyl chlorides with methyl iodide, which are then reacted with dimethyl acetylenedicarboxylate to form the desired product. The final step is to hydrolyze the ester group with hydrochloric acid to yield (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid. This chemical has been shown to have antibacterial properties against some strains of bacteria such as

• Brand: Biosynth

Chemical properties

• Molecular weight: 216.22 g/mol
• Formula: C₆H₈N₄O₃S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H8N4O3S/c1-2-13-9-3(5(11)12)4-8-6(7)14-10-4/h2H2,1H3,(H,11,12)(H2,7,8,10)/b9-3-
• InChI key: InChIKey=UFTDZEXQFNFPFR-OQFOIZHKSA-N
• SMILES: CCO/N=C(\C(=O)O)c1nsc(N)n1