3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide

CAS: 88919-22-6

Ref. 3D-FA33265

Product Information

• Name: 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide
• Synonyms: 1-[3-(2-Aminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide, 1H-Indole-5-methanesulfonamide, 3-(2-aminoethyl)-N-methyl-, 3-(2-Aminoethyl)-N-Methyl-1H-Indole-5-Methanesulfonamide

Description

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (AMIS) is an intermediate in the preparation of medicaments. It is a stable process and can be used as an intermediate for other compounds. AMIS is prepared by reacting methanesulfonic acid with methanol and ammonium carbonate, which produces methanesulfonamide, succinic acid and ammonium hydroxide. The reaction liquid is then heated to produce a crystalline solid. The crystals are then recrystallized to yield AMIS as a white solid.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.35 g/mol
• Formula: C₁₂H₁₇N₃O₂S
• Purity: Min. 95%
• Color/Form: Off-White To Beige To Light Brown Solid
• InChI: InChI=1S/C12H17N3O2S/c1-14-18(16,17)8-9-2-3-12-11(6-9)10(4-5-13)7-15-12/h2-3,6-7,14-15H,4-5,8,13H2,1H3
• InChI key: InChIKey=MURZXKIEJFJMPP-UHFFFAOYSA-N
• SMILES: CNS(=O)(=O)Cc1ccc2[nH]cc(CCN)c2c1