Z-L-Asp-OH

CAS: 1152-61-0

Ref. 3D-FA36771

Product Information

• Name: Z-L-Asp-OH
• Synonyms: (2S)-2-(Phenylmethoxycarbonylamino)butanedioic acid, (2S)-2-[[(Benzyloxy)carbonyl]amino]butanedioic acid, (2S)-2-{[(benzyloxy)carbonyl]amino}butanedioate, <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, Aspartic acid, N-carboxy-, N-benzyl ester, Aspartic acid, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-, Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid, CBZ-L-Aspartic Acid-OH, Carbobenzoxy-<span class="text-smallcaps">L</span>-aspartic acid, Cbz-Asp-OH, Cbz-L-aspartic acid, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-aspartic acid, N-Benzyloxycarbonyl-L-aspartic acid, N-Benzyloxylcarbonyl-<span class="text-smallcaps">L</span>-aspartic acid, N-CBZ-L-Aspartic acid N-Carbobenzyloxy-L-aspartic acid, N-Carbobenzoxy-<span class="text-smallcaps">L</span>-aspartic acid, N-Carbobenzoxy-L-aspatic acid, N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-aspartic acid, N-Cbz-L-Asp-OH, N-Cbz-L-aspartic acid, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartic acid, N-[(benzyloxy)carbonyl]-D-aspartic acid, N-[(benzyloxy)carbonyl]-L-aspartic acid, N-[(benzyloxy)carbonyl]aspartic acid, N-cbz-L-aspartic acid crystalline, NALPHA-Benzyloxycarbonyl-L-aspartic acid, NSC 88479, NSC 9972, Z-Asp-OH, Z-L-Aspartic acid, z-Asp, Carbobenzoxy-L-aspartic acid, N-[(Phenylmethoxy)carbonyl]-L-aspartic acid, Aspartic acid, N-carboxy-, N-benzyl ester, L-, L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-

Description

Z-L-Asp-OH is a protease inhibitor that inhibits the activity of serine proteases, including trypsin and chymotrypsin. Z-L-Asp-OH binds to the active site of these enzymes and prevents them from cleaving their substrates. The optimal pH for this enzyme is 8.0, which corresponds to its maximum level of activity. Z-L-Asp-OH also has apoptotic activities in cells by causing cellular pathway changes, leading to cell death via programmed cell death or apoptosis. This agent is activated by hydrolysis at ester linkages and polymerizes into films in aqueous solution at physiological pH. It has been shown to inhibit the growth of human ovarian carcinoma cells in vitro, but not normal cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.23 g/mol
• Formula: C₁₂H₁₃NO₆
• Purity: Min. 95%
• InChI: InChI=1S/C12H13NO6/c14-10(15)6-9(11(16)17)13-12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,18)(H,14,15)(H,16,17)/t9-/m0/s1
• InChI key: InChIKey=XYXYXSKSTZAEJW-VIFPVBQESA-N
• SMILES: O=C(O)C[C@H](NC(=O)OCc1ccccc1)C(=O)O