Z-DL-Ala-OH

CAS: 4132-86-9

Ref. 3D-FA36827

Product Information

• Name: Z-DL-Ala-OH
• Synonyms: (2R)-2-{[(benzyloxy)carbonyl]amino}propanoate, 2-[(Benzyloxycarbonyl)amino]propanoic acid, <span class="text-smallcaps">DL</span>-(Carbobenzyloxy)alanine, <span class="text-smallcaps">DL</span>-Alanine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">DL</span>-Cbz alanine, Alanine, N-[(phenylmethoxy)carbonyl]-, Alanine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">DL</span>-, Benzyloxycarbonyl-<span class="text-smallcaps">DL</span>-alanine, Cbz-DL-alanine, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">DL</span>-alanine, N-Benzoxycarbonyl-<span class="text-smallcaps">DL</span>-alanine, N-Carbobenzoxy-<span class="text-smallcaps">DL</span>-alanine, N-Carbobenzyloxy-<span class="text-smallcaps">DL</span>-alanine, N-Cbz-<span class="text-smallcaps">DL</span>-alanine, N-[(Phenylmethoxy)carbonyl]alanine, N-[(benzyloxy)carbonyl]alanine, NSC 27684, Z-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-Ala-OH, z-Dl-Ala, N-(Benzyloxycarbonyl)-DL-alanine, Alanine, N-carboxy-, N-benzyl ester, DL-, DL-Alanine, N-carboxy-, N-benzyl ester

Description

Z-DL-Ala-OH is a hydration inhibitor that binds to the active site of enzymes and blocks the catalysis of their substrates. It has been shown to inhibit enzymes such as cytosolic Ca2+-ATPase, butanol dehydrogenase, and acetylcholinesterase. Z-DL-Ala-OH also has anti-inflammatory effects and may be used for the treatment of epilepsy. Z-DL-Ala-OH inhibits the production of cytosolic Ca2+, which leads to a decrease in intracellular free Ca2+ ions and an increase in free Mg2+ ions. This change in ionic balance inhibits the activity of proton pumps, leading to inhibition of neurotransmitter release. The molecular modeling study showed that Z-DL-Ala-OH binds well to carbamazepine’s binding site on the enzyme with high affinity, suggesting that it could be used as a drug for treating epilepsy

• Brand: Biosynth

Chemical properties

• Molecular weight: 223.23 g/mol
• Formula: C₁₁H₁₃NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)
• InChI key: InChIKey=TYRGLVWXHJRKMT-UHFFFAOYSA-N
• SMILES: CC(NC(=O)OCc1ccccc1)C(=O)O