3-Amino-4-cyanopyridine
CAS: 78790-79-1
Ref. 3D-FA38514
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 500mg | To inquire |
Product Information
- 3-Aminoisonicotinonitrile
- 3-Aminopyridine-4-Carbonitrile
- 3-Amino-4-Cyano-Pyridine
3-Amino-4-cyanopyridine is an anticancer agent that is a potent inhibitor of DNA topoisomerase II. This compound binds to the enzyme and prevents it from breaking and rejoining the strands of DNA, which leads to cell death. 3-Amino-4-cyanopyridine has been shown to be a selective inhibitor of cancer cells with low toxicity for healthy cells. It also inhibits the growth of leukemia cells by inhibiting DNA synthesis, protein synthesis, and RNA synthesis. 3-Amino-4-cyanopyridine has been shown to have a high affinity for indole-7-carbonitrile (ICL), which is a ligand found in many anticancer drugs. The interactions between ICL and 3ACN are studied using silico molecular docking simulations.
Chemical properties
Technical inquiry about: 3D-FA38514 3-Amino-4-cyanopyridine
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