Aloc-OSu

CAS: 135544-68-2

Ref. 3D-FA38529

Product Information

• Name: Aloc-OSu
• Synonyms: Aloc-Osu, 1-{[(Prop-2-En-1-Yloxy)Carbonyl]Oxy}Pyrrolidine-2,5-Dione, Aloc-Osu Allyloxycarbonyl Succinimidyl Ester

Description

Aloc-OSu is a glycosylated glycopeptide antibiotic that belongs to the class of degradable antibiotics. The drug binds to the enzyme UDP-N-acetylglucosamine:glycoprotein glucosyltransferase, thereby inhibiting bacterial cell wall synthesis. Aloc-OSu has been shown to be effective against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Aloc-OSu has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 199.16 g/mol
• Formula: C₈H₉NO₅
• Purity: Min. 95%
• InChI: InChI=1S/C8H9NO5/c1-2-5-13-8(12)14-9-6(10)3-4-7(9)11/h2H,1,3-5H2
• InChI key: InChIKey=OIXALTPBNZNFLJ-UHFFFAOYSA-N
• SMILES: C=CCOC(=O)ON1C(=O)CCC1=O