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5-Amino-8-hydroxyquinoline dihydrochloride
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5-Amino-8-hydroxyquinoline dihydrochloride

CAS: 21302-43-2

Ref. 3D-FA40514

2g
172.00 €
5g
348.00 €
10g
518.00 €
25g
863.00 €
50g
1,392.00 €
Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
5-Amino-8-hydroxyquinoline dihydrochloride
Synonyms:
  • 5-Amino-8-Hydroquinoline Dihydrochloride
  • 5-Amino-8-Hydroxyquinoline Dihydrochloride
  • 5-Amino-8-Hydroxyquinoline Dihydrochloride 97+%
  • 5-Amino-8-Hydroxyquinoline2Hcl
  • 5-Amino-8-Quinolinol Dihydrochloride
  • 5-Aminoquinolin-8-Ol Dihydrochloride
  • 8-Quinolinol, 5-Amino-, Dihydrochloride
  • 8-Quinolinol, 5-amino-, hydrochloride (1:2)
Description:

5-Amino-8-hydroxyquinoline dihydrochloride (5-AQDH) is an anticancer drug that inhibits the activity of survivin, a protein that is overexpressed in cancer cells. It has been shown to be effective in vivo against melanoma tumor growth. 5-AQDH binds to the unpaired cysteine residues of the survivin molecule and inhibits its function by binding to the active site, blocking access to ATP and preventing DNA synthesis. The efficacy of 5-AQDH has been confirmed in vitro by studying the effect on cell viability and DNA synthesis, as well as by measuring plasma mass spectrometry data from melanoma patients. This drug is currently being investigated for its potential use as an anticancer agent.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
212.63 g/mol
Formula:
C9H8N2O•(HCl)2
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
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Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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