2-Amino-5-iodobenzoic acid

CAS: 5326-47-6

Ref. 3D-FA52328

Product Information

• Name: 2-Amino-5-iodobenzoic acid
• Synonyms: 5-Iodoanthranilic acid, 2-Amino-5-Iodobenzoate, 2-Amino-5-iodo-benzoic acid, 2-Amio-5-iodobenzoic acid, 5-Iodo-2-aminobenzoic acid, 5-Iodoanthranillic acid, Anthranilic acid, 5-iodo-, Benzoic acid, 2-amino-5-iodo-, NSC 302

Description

2-Amino-5-iodobenzoic acid (5-AIBA) is a chemical compound with a molecular weight of 152.14 g/mol. It belongs to the group of anthranilic compounds, and has antiinflammatory activity. 5-AIBA also inhibits cancer cell proliferation in vitro and in vivo by inhibiting the synthesis of DNA, RNA, and proteins. The reaction solution for the palladium-catalyzed coupling of 5-AIBA with 2-(N,N′-dimethylcarbamoyl)phenyl boronic acid was found to be stable at room temperature for 24 hours. The inhibitory activity of 5-AIBA against MCL1 protein was potent, as it inhibited MCL1 protein expression by 90%. Molecular modeling studies showed that 5-AIBA binds to the amide region on the ATP binding site in MCL1 protein (mcf7). Carbonyl groups are present on both sides of the am

• Brand: Biosynth

Chemical properties

• Molecular weight: 263.03 g/mol
• Formula: C₇H₆INO₂
• Purity: Min. 98 Area-%
• Color/Form: Powder