3-Amino-2-hydroxybenzoic acid

CAS: 570-23-0

Ref. 3D-FA54934

Product Information

• Name: 3-Amino-2-hydroxybenzoic acid
• Synonyms: 3-Aminosalicylic acid, 2-Hydroxy-3-aminobenzoic acid, 3-Amino Salicylate, 3-Amino-2-Hydroxy-Benzoate, 3-Amino-2-hydroxybenzoate, 3-Aminosalicylate, Benzoic acid, 3-amino-2-hydroxy-, NSC 285111, Salicylic acid, 3-amino-, Tci-A 0421

Description

3-Amino-2-hydroxybenzoic acid (AAHB) is a nonsteroidal anti-inflammatory drug that belongs to the group of pharmaceutical preparations. It inhibits the enzyme dehydroascorbate reductase, which is involved in the production of hydrogen peroxide and other reactive oxygen species by phagocytes. Hydrogen peroxide and other reactive oxygen species can cause DNA damage and lead to cancer development. AAHB may also have antimicrobial effects, as it has been shown to inhibit bacterial growth and cell adhesion. AAHB interacts with fatty acids in a similar manner as aspirin does, but with a lower potency. It has been shown to inhibit prostaglandin synthesis by inhibiting lipoxygenase activity. The binding of AAHB at these sites prevents the formation of arachidonic acid from linoleic acid and blocks the conversion of arachidonic acid into prostaglandin H2 (PGH2).

• Brand: Biosynth

Chemical properties

• Molecular weight: 153.14 g/mol
• Formula: C₇H₇NO₃
• Purity: Min. 98 Area-%
• Color/Form: Off-White Powder