2-Amino-5-iodobenzoic acid methyl ester
CAS: 77317-55-6
Ref. 3D-FA55376
| 5g | 88.00 € | ||
| 25g | 193.00 € | ||
| 50g | 353.00 € | ||
| 100g | 504.00 € | ||
| 250g | 971.00 € |
Product Information
- Methyl 2-amino-5-iodobenzoate 5-Iodoanthranilic acid methyl ester
- 5-Iodoanthranilic acid methyl ester
- Anthranilic acid, 5-iodo-, methyl ester
- Benzoic acid, 2-amino-5-iodo-, methyl ester
- Methyl 2-Amino-5-Iodobenzoate
- Methyl 5-iodoanthranilate
2-Amino-5-iodobenzoic acid methyl ester (2AIBA) is a molecule that can be used as an activatable probe for imaging cancer. It has a profile suitable for radionuclide therapy and is also senescent. 2AIBA binds to DNA and inhibits the synthesis of proteins, leading to cell death. 2AIBA has potent inhibitory activity against murine melanoma cells and synergistic effects when combined with acridone. The section of tumour cells was shown to be reduced by 42% in mice when treated with 2AIBA, acridone, and radiation compared to mice treated with radiation alone.
Chemical properties
Technical inquiry about: 3D-FA55376 2-Amino-5-iodobenzoic acid methyl ester
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