4-Amino-3-bromopyridine

Ref. 3D-FA55436

Product Information

• Name: 4-Amino-3-bromopyridine
• Synonyms: 3-Bromo-4-aminopyridine
• Brand: Biosynth
• Description: 4-Amino-3-bromopyridine is an isomer of pyridine, which has been synthesized to serve as a substrate for nucleoside phosphorylase, the enzyme that catalyzes the conversion of inorganic phosphate and nucleoside diphosphate into ribonucleoside diphosphate. 4-Amino-3-bromopyridine has been shown to inhibit the activity of this enzyme with an IC50 value of 0.44 mM and competitively inhibits the binding of ATP with a Ki value of 1.0 mM. The use of 4-amino-3-bromopyridine as a substrate for nucleoside phosphorylase may be used as a novel strategy to treat diseases involving genetic defects in the DNA or RNA synthesis pathways.

Chemical properties

• Molecular weight: 173.01 g/mol
• Formula: C₅H₅BrN₂
• Purity: Min. 95%