4-Amino-3-bromopyridine
CAS: 13534-98-0
Ref. 3D-FA55436
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 10g | To inquire | ||
| 25g | To inquire |
Product Information
- 3-Bromo-4-aminopyridine
- 3-Bromo-4-pyridinamine
- 3-Bromopyridin-4-Amine
- 4-Amino-3-Bromopyridinium
- 3-Bromo-pyridin-4-ylamine
4-Amino-3-bromopyridine is an isomer of pyridine, which has been synthesized to serve as a substrate for nucleoside phosphorylase, the enzyme that catalyzes the conversion of inorganic phosphate and nucleoside diphosphate into ribonucleoside diphosphate. 4-Amino-3-bromopyridine has been shown to inhibit the activity of this enzyme with an IC50 value of 0.44 mM and competitively inhibits the binding of ATP with a Ki value of 1.0 mM. The use of 4-amino-3-bromopyridine as a substrate for nucleoside phosphorylase may be used as a novel strategy to treat diseases involving genetic defects in the DNA or RNA synthesis pathways.
Chemical properties
Technical inquiry about: 3D-FA55436 4-Amino-3-bromopyridine
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