2-Aminoindane-2-carboxylic acid

CAS: 27473-62-7

Ref. 3D-FA56052

Product Information

• Name: 2-Aminoindane-2-carboxylic acid
• Synonyms: Aic-OH, 1H-indene-2-carboxylic acid, 2-amino-2,3-dihydro-, 2-Amino-2-indancarboxylicacid, 2-Amino-2-Indancarboxylic acid

Description

2-Aminoindane-2-carboxylic acid is a potent opioid analgesic with a high affinity for kappa-opioid receptors. Molecular modeling studies suggest that it binds to the receptor in an orientation similar to morphine and has a higher binding affinity than morphine. In functional assays, 2-Aminoindane-2-carboxylic acid showed low potency at the delta opioid receptor. It also has been shown to have a high affinity for the kappa opioid receptor and a low affinity for delta opioid receptors, which are associated with respiratory depression. This drug can be made from indole and carboxylic acids or by treating 2 aminoindanone with hydrochloric acid and hydrogen gas.

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.2 g/mol
• Formula: C₁₀H₁₁NO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H11NO2/c11-10(9(12)13)5-7-3-1-2-4-8(7)6-10/h1-4H,5-6,11H2,(H,12,13)
• InChI key: InChIKey=UHQFXIWMAQOCAN-UHFFFAOYSA-N
• SMILES: NC1(C(=O)O)Cc2ccccc2C1