Amoxicillin trihydrate impurity K

CAS: 210289-72-8

Ref. 3D-FA63624

Product Information

• Name: Amoxicillin trihydrate impurity K
• Synonyms: Amoxicillin dimer(2R)-(2R)-2-[(2R,4S)Thyl-2-thiazolidinyl]glycyl-(2R)-2-(4-hydroxyphenyl)glycyl-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2 -thiazolidinyl]glycine
• Brand: Biosynth
• Description: Amoxicillin trihydrate impurity K is an analytical impurity that is found as a sodium salt in amoxicillin sodium. The impurity can be identified by a titration method, which involves the use of phenolphthalein. This product has been shown to have antimicrobial activity against both Gram-positive and Gram-negative bacteria. Impurity K is produced during the synthetic process, which consists of the following steps: 1) Amoxicillin sodium is dissolved in water and then treated with glycopeptide (glycine), 2) The mixture is heated in order to hydrolyze glycopeptide into glycocoll and N-acetylglycocoll, 3) The mixture is then cooled to produce two layers - an upper layer consisting of water and glycocoll, and a lower layer consisting of N-acetylglycocoll, 4) The upper layer is drained off and purified using liquid chromatography.

Chemical properties

• Molecular weight: 748.83 g/mol
• Formula: C₃₂H₄₀N₆O₁₁S₂
• Purity: Min. 95%