3-Amino-4-methoxybenzamide

CAS: 17481-27-5

Ref. 3D-FA64884

Product Information

• Name: 3-Amino-4-methoxybenzamide
• Synonyms: (3-Amino-4-methoxybenzoyl)amine, 3-Amino-4-Methoxy-Benzamide, 3-Amino-4-anisamide, 3-Amino-4-methoxybenzenecarboxamide, 3-Amino-4-methoxybenzoic acid amide, Benzamide, 3-amino-4-methoxy-, Db-20, Fast Red Base KL, p-Anisamide, 3-amino-, C.I.Azoic Diazo Component 121

Description

3-Amino-4-methoxybenzamide (3AMB) is a transcriptional regulator that inhibits the expression of genes encoding for the synthesis of aminoglycoside antibiotics. 3AMB binds to DNA, forming a heteromer with the transcription factor HANATX, which prevents RNA polymerase from binding to DNA. This in turn inhibits gene expression and bacterial growth. 3AMB has been shown to trigger diabetic neuropathy by inhibiting xylitol dehydrogenase, an enzyme required for neuron protection against oxidative stress. The drug also has a high affinity for nucleophiles and can bind to various substrates such as sulfhydryl groups or hydroxyl groups.

• Brand: Biosynth

Chemical properties

• Molecular weight: 166.18 g/mol
• Formula: C₈H₁₀N₂O₂
• Purity: Min. 98%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C8H10N2O2/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4H,9H2,1H3,(H2,10,11)
• InChI key: InChIKey=INCJNDAQNPWMPZ-UHFFFAOYSA-N
• SMILES: COc1ccc(C(N)=O)cc1N