Acetylshikonin

CAS: 24502-78-1

Ref. 3D-FA65519

Product Information

• Name: Acetylshikonin
• Synonyms: (1R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl acetate, (R)-1-(5,8-Dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl acetate, 1,4-Naphthalenedione, 2-[(1R)-1-(acetyloxy)-4-methyl-3-penten-1-yl]-5,8-dihydroxy-, 1,4-Naphthalenedione, 2-[(1R)-1-(acetyloxy)-4-methyl-3-pentenyl]-5,8-dihydroxy-, 1,4-Naphthalenedione, 2-[1-(acetyloxy)-4-methyl-3-pentenyl]-5,8-dihydroxy-, (R)-, 1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, 2-acetate, (+)-, 1-(5,8-Dihydroxy-1,4-Dioxo-1,4-Dihydronaphthalen-2-Yl)-4-Methylpent-3-En-1-Yl Acetate, 2-[(1R)-1-(Acetyloxy)-4-methyl-3-penten-1-yl]-5,8-dihydroxy-1,4-naphthalenedione, NSC 110199

Description

Acetylshikonin is a natural compound that belongs to the group of growth factors. It has been shown to inhibit the proliferation of 3T3-L1 preadipocytes, which are cells in the body that store fat and produce hormones. Acetylshikonin also inhibits the production of p-hydroxybenzoic acid, which is an important intermediate for cellular metabolism. The optimal concentration for acetylshikonin was determined using preparative high-performance liquid chromatography (HPLC). This compound has been found to induce apoptosis by activating caspase-3 and -9, as well as other pathways in vitro studies on cancer cells. Acetylshikonin also has significant cytotoxicity and anti-inflammatory properties. The surfactant sodium dodecyl sulfate (SDS) was used to extract acetylshikonin from plant material. Acetylshikonin can be detected by analytical

• Brand: Biosynth

Chemical properties

• Molecular weight: 330.33 g/mol
• Formula: C₁₈H₁₈O₆
• Purity: Min. 98 Area-%
• Color/Form: Brown Powder
• InChI: InChI=1S/C18H18O6/c1-9(2)4-7-15(24-10(3)19)11-8-14(22)16-12(20)5-6-13(21)17(16)18(11)23/h4-6,8,15,20-21H,7H2,1-3H3/t15-/m1/s1
• InChI key: InChIKey=WNFXUXZJJKTDOZ-OAHLLOKOSA-N
• SMILES: CC(=O)O[C@H](CC=C(C)C)C1=CC(=O)c2c(O)ccc(O)c2C1=O