Androstane

CAS: 438-22-2

Ref. 3D-FA66020

Product Information

• Name: Androstane
• Synonyms: 5alpha-AndrostaneEtioallocholane, (5Alpha,8Alpha,9Beta,13Alpha,14Beta)-Androstane, 5alpha,14alpha-Androstane, 5alpha-Androstane, 5α,14α-Androstane, 5α-Androstan, Aetioallocholane, Androstane, (5alpha)-, Androstane, (5α)-, Etioallocholane, Nsc 49000, (5α)-Androstane, 5α-Androstane

Description

Androstane is a human nuclear steroid that has been found to be a constitutive androstane receptor ligand at physiological levels. Androstane has been shown to regulate transcriptional activity through the androgen receptor. It is also an endogenous metabolite of testosterone, with both anti-inflammatory and immunosuppressive effects. Androstane has shown efficacy against infectious diseases such as malaria, which is caused by a protozoan parasite that invades red blood cells. This compound is also used in drug transporter studies, where it has been shown to inhibit the P-glycoprotein efflux pump in cancer cells, leading to increased accumulation of anticancer drugs in tumor cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 260.46 g/mol
• Formula: C₁₉H₃₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14-,15+,16+,17+,18+,19+/m1/s1
• InChI key: InChIKey=QZLYKIGBANMMBK-UGCZWRCOSA-N
• SMILES: C[C@@]12CCC[C@H]1[C@@H]1CC[C@H]3CCCC[C@]3(C)[C@H]1CC2