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5-Aminopyridine-3-carboxylic acid

CAS:

Ref. 3D-FA66664

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5-Aminopyridine-3-carboxylic acid
Biosynth

Product Information

Name:5-Aminopyridine-3-carboxylic acid
Synonyms:
  • 5-Aminonicotinic acid
Brand:Biosynth
Description:5-Aminopyridine-3-carboxylic acid (5APC) is a structural analog of nicotinic acid that has been shown to have anti-inflammatory effects. 5APC inhibits the production of inflammatory cytokines, such as IL-10 and IL-17, by inhibiting the activation of NFκB and MAPK pathways. This drug also has significant inhibitory activities against dextran sulfate sodium (DSS)-induced acute colitis in experimental models. 5APC is thought to act by interrupting the assembly of p38 mitogen activated protein kinase (MAPK) and nuclear factor kappa B (NFκB) signaling complexes.
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Chemical properties

Molecular weight:138.12 g/mol
Formula:C6H6N2O2
Purity:Min. 95%
InChI:InChI=1S/C6H6N2O2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,7H2,(H,9,10)
InChI key:InChIKey=BYIORJAACCWFPU-UHFFFAOYSA-N
SMILES:Nc1cncc(C(=O)O)c1

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