Product Information
- 2-acetyl-4-nitro-1H-indene-1,3(2H)-dione
2-Acetyl-4-nitroindane-1,3-dione is a synthetic compound that is assembled in two steps from commercially available starting materials. The first step involves the assembly of the nitro group and acetyl group on the indane ring. The second step involves the oxidative cyclization of the nitro group to form the final product. The compound was monitored by UV absorption and HPLC analysis with a spermidine standard. It has been shown to selectively inhibit trypanothione reductase, an enzyme involved in trypanosome metabolism. 2-Acetyl-4-nitroindane-1,3-dione is also an analogue of disulphide, which has been shown to be effective against trypanosomes. 2-Acetyl-4-nitroindane-1,3-dione is synthesized on solid phase using strategies developed for peptides and amines. This compound has also
Chemical properties
Technical inquiry about: 3D-FA66807 2-Acetyl-4-nitroindane-1,3-dione
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