2-Amino-9-fluorenol

CAS: 33417-27-5

Ref. 3D-FA66891

Product Information

• Name: 2-Amino-9-fluorenol
• Synonyms: 2-Amino-9-Fluorenone, 2-amino-9H-fluoren-9-ol, 9H-Fluoren-9-ol, 2-amino-, Fluoren-9-ol, 2-amino-, NSC 12389

Description

2-Amino-9-fluorenol is a hydrophobic compound that binds to RNA. 2-Amino-9-fluorenol has been shown to have a binding constant of 1.2 x 10, which is much higher than the binding constant for curculigoside (5.2 x 10). This substance has shown to be an effective inhibitor of RNA synthesis in HL60 cells and various bacterial strains by binding to the ribose moiety of RNA and preventing transcription. The metabolic pathway for 2-amino-9-fluorenol consists of two steps: one involving a reactive intermediate, potassium ion, and another with methylamine as the reactant. These reactions are catalyzed by enzymes such as acetaldehyde dehydrogenase and amino transferases, respectively.

• Brand: Biosynth

Chemical properties

• Molecular weight: 197.23 g/mol
• Formula: C₁₃H₁₁NO
• Purity: Min. 95%
• Color/Form: Yellow solid.
• InChI: InChI=1S/C13H11NO/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)12(10)7-8/h1-7,13,15H,14H2
• InChI key: InChIKey=TWLNNLHYUBGLHG-UHFFFAOYSA-N
• SMILES: Nc1ccc2c(c1)C(O)c1ccccc1-2