3-(Aminomethyl)phenol

CAS: 73604-31-6

Ref. 3D-FA70624

Product Information

• Name: 3-(Aminomethyl)phenol
• Synonyms: 3-Hydroxybenzylamine, Phenol, 3-(aminomethyl)-, m-Hydroxybenzylamine
• CAS: 73604-31-6

Description

3-(Aminomethyl)phenol is a potent inhibitor of growth factor receptor kinase (GRK) and protein kinase C. It has been shown to have inhibitory effects on cellular proliferation in mammalian cells and is being investigated as an adjuvant therapy for cancer treatment. 3-(Aminomethyl)phenol has also been shown to inhibit the enzyme cyclooxygenase-2, which is involved in the synthesis of prostaglandins.
DISCUSSION: The carbonyl group of 3-(aminomethyl)phenol makes it a potent inhibitor of GRKs and protein kinases C. Kinases are enzymes that catalyze the addition of phosphate groups onto proteins, which affects their activity. As such, 3-(aminomethyl)phenol inhibits the activity of GRKs and protein kinases C by binding to the ATP-binding site, preventing ATP from binding and phosphorylating the enzyme's target proteins

• Brand: Biosynth

Chemical properties

• Molecular weight: 123.15 g/mol
• Formula: C₇H₉NO
• Purity: Min. 95%
• InChI: InChI=1S/C7H9NO/c8-5-6-2-1-3-7(9)4-6/h1-4,9H,5,8H2
• InChI key: InChIKey=JNZYADHPGVZMQK-UHFFFAOYSA-N
• SMILES: NCc1cccc(O)c1