7-Amino-4-(trifluoromethyl)coumarin

CAS: 53518-15-3

Ref. 3D-FA74300

Product Information

• Name: 7-Amino-4-(trifluoromethyl)coumarin
• Brand: Biosynth

Description

7-Amino-4-(trifluoromethyl)coumarin is a coumarin derivative that has been used as a fluorescence probe for the study of enzyme activities. It can be used as a potential biomarker for autoimmune diseases, and has also been shown to have tyrosine kinase domain binding activity. 7-Amino-4-(trifluoromethyl)coumarin can bind to the hydroxyl group in tyrosine residues with high affinity, and binds to the nitrogen atoms in protein kinases with low affinity. This compound is able to form intermolecular hydrogen bonds and steric interactions with peptide hormones.

Chemical properties

• Molecular weight: 229.16 g/mol
• Formula: C₁₀H₆F₃NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2
• InChI key: InChIKey=JBNOVHJXQSHGRL-UHFFFAOYSA-N
• SMILES: Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1