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6-Aza-2-thiothymine
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6-Aza-2-thiothymine

CAS: 615-76-9

Ref. 3D-FA76662

2g
189.00 €
5g
341.00 €
10g
456.00 €
25g
905.00 €
50g
1,620.00 €
Estimated delivery in United States, on Tuesday 17 Dec 2024

Product Information

Name:
6-Aza-2-thiothymine
Synonyms:
  • 1,2,4-Triazin-5(2H)-one, 3,4-dihydro-6-methyl-3-thioxo-
  • 1,2,4-Triazin-5(2H)-one, 3,4-dihydro-6-methyl-3-thioxo- (9CI)
  • 2-Thio-6-azathymine
  • 3,4-Dihydro-6-methyl-3-thioxo-1,2,4-triazin-5(2H)-one
  • 3-Mercapto-5-hydroxy-6-methyl-1,2,4-triazine
  • 3-Mercapto-6-methyl-1,2,4-triazin-5(4H)-one
  • 3-Mercapto-6-methyl-1,2,4-triazin-5-ol
  • 3-Mercapto-6-methyl-as-triazin-5-ol
  • 5-Methyl-2-thio-6-azauracil
  • 6-Methyl-3-thio-as-triazine-3,5(2H,4H)-dione
  • See more synonyms
  • 6-methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one
  • Nsc 102906
  • Nsc 1609
  • Nsc 38618
  • as-Triazin-5-ol, 3-mercapto-6-methyl-
  • as-Triazine-3,5(2H,4H)-dione, 6-methyl-3-thio-
  • as-Triazine-3,5(2H,4H)-dione, 6-methyl-3-thio- (8CI)
Description:

6-Aza-2-thiothymine is a hydrophobic base that is used in the preparation of DNA sequencing samples. It can be incorporated into DNA by enzymatic reactions with picolinic acid, which results in an increase in the number of thiol groups on the DNA. The incorporation of 6-aza-2-thiothymine into DNA is detected by binding to malonic acid and subsequent detection by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The presence of 6-aza-2-thiothymine can also be detected using a photochemical reaction with hydroxyl radicals, resulting in a change in the fluorescence properties of oligosaccharides bound to the DNA. This compound has been shown to inhibit prostate cancer cells and may be useful as a treatment for this type of cancer.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
143.17 g/mol
Formula:
C4H5N3OS
Color/Form:
White Powder
InChI:
InChI=1S/C4H5N3OS/c1-2-3(8)5-4(9)7-6-2/h1H3,(H2,5,7,8,9)
InChI key:
InChIKey=NKOPQOSBROLOFP-UHFFFAOYSA-N
SMILES:
Cc1n[nH]c(=S)[nH]c1=O
MDL:
Melting point:
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Flash point:
Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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