N-Boc-3-Azetidinol

CAS: 141699-55-0

Ref. 3D-FB04741

Product Information

• Name: N-Boc-3-Azetidinol
• Synonyms: 1-N-Boc-3-hydroxyazetidine, Buttpark 75\04-65, 3-Hydroxyazetidine, N-Boc Protected, 3-Hydroxy-Azetidine-1-Carboxylic Acid Tert-Butyl Ester, 1-Boc-3-(Hydroxy)Azetidine, Tert-Butyl 3-Hydroxyazetidine-1-Carboxylate, N-Boc-3-Hydroxyazetidine, 1-Tert-Butoxycarbonyl-3-Azetidinol, 1-Boc-3-Hydroxyazetidine, N-Boc-3-A

Description

N-Boc-3-Azetidinol is an azetidine-based drug that is synthesized from 3-hydroxyazetidine hydrochloride. It has been shown to be a good substrate for the preparation of N-protected amino alcohols and amines by the process of reductive amination. In this synthesis, tert-butyl azetidinium chloride is used as a catalyst in the reaction with sodium hydroxide. The tert-butyl group can be removed using ammonium hydroxide in the presence of a base such as triethylamine. This reaction can be performed on a large scale, making it useful in the manufacture of pharmaceuticals. The efficiency and solubility of this process make it suitable for use as an introduction to other processes involving N-protected amino alcohols or amines.END>>

• Brand: Biosynth

Chemical properties

• Molecular weight: 173.21 g/mol
• Formula: C₈H₁₅NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C8H15NO3/c1-8(2,3)12-7(11)9-4-6(10)5-9/h6,10H,4-5H2,1-3H3
• InChI key: InChIKey=XRRXRQJQQKMFBC-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CC(O)C1