8-Bromoguanine

CAS: 3066-84-0

Ref. 3D-FB08785

Product Information

• Name: 8-Bromoguanine
• Synonyms: 2-Amino-8-bromo-1,7-dihydropurin-6-one2-Amino-8-bromo-7H-purin-6-ol, 6H-Purin-6-one, 2-amino-8-bromo-1,7-dihydro-, 2-Amino-8-bromo-1,9-dihydro-6H-purin-6-one, 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-, Guanine, 8-bromo-

Description

8-Bromoguanine is a nucleoside analog drug that is used as an antileukemic agent. It is a synthetic derivative of guanine and has been shown to inhibit the growth of leukemic cells by interfering with the synthesis of DNA. 8-Bromoguanine has also been shown to be reactive with eosinophil peroxidase and other electron-rich substances, which may be due to its hydroxyl group. The analytical method for 8-bromoguanine includes fluorescence spectroscopy, high pressure liquid chromatography (HPLC), and thin layer chromatography (TLC). Chemical diversity studies have shown that 8-bromoguanine can react with glycosylase or hydroxy groups, forming reaction products.

• Brand: Biosynth

Chemical properties

• Molecular weight: 230.02 g/mol
• Formula: C₅H₄BrN₅O
• Purity: Min. 97 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C5H4BrN5O/c6-4-8-1-2(9-4)10-5(7)11-3(1)12/h(H4,7,8,9,10,11,12)
• InChI key: InChIKey=CRYCZDRIXVHNQB-UHFFFAOYSA-N
• SMILES: Nc1nc2nc(Br)[nH]c2c(=O)[nH]1