1,3-Bis[tris(hydroxymethyl)methylamino]propane

CAS: 64431-96-5

Ref. 3D-FB09448

Product Information

• Name: 1,3-Bis[tris(hydroxymethyl)methylamino]propane
• Synonyms: BIS-TRIS propane, 1,3-Bis(tris(hydroxymethyl)methyl amino)propane, 1,3-Bis[1,1-bis(hydroxymethyl)-2-hydroxyethylamino]propane, 1,3-Bis[Tris(hydroxyethyl)methylamino]Propane, 1,3-Propanediol, 2,2′-(1,3-propanediyldiimino)bis[2-(hydroxymethyl)-, 2,2'-(Propane-1,3-Diyldiimino)Bis[2-(Hydroxymethyl)Propane-1,3-Diol], 2,2′-(1,3-Propanediyldiimino)bis[2-(hydroxymethyl)-1,3-propanediol], 2-[3-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propylamino]-2-(hydroxymethyl)propane-1,3-diol, BIS-Tris Propane, ULTROL Grade, Bis Tris propane 1,3-Bis[tris(hydroxymethyl)methylamino]propane, Bis-Tris Propane Molecular Biology*Reagent, Bistrishydroxymethylmethylaminopropane, NSC 610927

Description

1,3-Bis[tris(hydroxymethyl)methylamino]propane is a compound that has been shown to inhibit the growth of prostate cancer cells in tissue culture. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is used to extract and purify DNA from biological samples. It binds to DNA by electrostatic interactions with the phosphate groups on the nucleotide backbone, which induces cell lysis. This molecule has also been shown to be an inhibitor of polymerase chain reaction (PCR), a technique used for amplifying target sequences in DNA. The redox potential of this molecule can be measured using cyclic voltammetry. The compound also reacts with monoclonal antibodies specific for prostate cancer cells and inhibits their binding to prostate cancer cells.
1,3-Bis[tris(hydroxymethyl)methylamino]propane is a reactive compound that contains a

• Brand: Biosynth

Chemical properties

• Molecular weight: 282.3 g/mol
• Formula: C₁₁H₂₆N₂O₆
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
• InChI key: InChIKey=HHKZCCWKTZRCCL-UHFFFAOYSA-N
• SMILES: OCC(CO)(CO)NCCCNC(CO)(CO)CO