4,4'-Bis(hydroxymethyl)-2,2-bipyridine

CAS: 109073-77-0

Ref. 3D-FB10299

Product Information

• Name: 4,4'-Bis(hydroxymethyl)-2,2-bipyridine
• Synonyms: 2,2'-Bipyridine-4,4'-dimethanol, [2,2'-Bipyridine]-4,4'-Dimethanol, 2,2'-Bipyridine-4,4'-diyldimethanol
• CAS: 109073-77-0

Description

4,4'-Bis(hydroxymethyl)-2,2-bipyridine is a replication inhibitor that has been used in the treatment of cancer. It has also been shown to be effective in the treatment of metabolic disorders and chronic bronchitis. 4,4'-Bis(hydroxymethyl)-2,2-bipyridine binds to the active site of human HMG-CoA reductase, which is an enzyme involved in cholesterol synthesis. This binding prevents the formation of HMG-CoA, preventing the conversion of acetyl coenzyme A into cholesterol. The drug also binds to microbial metabolism enzymes such as fatty acid synthase and alkanoic acid oxidoreductases and has significant cytotoxicity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 216.24 g/mol
• Formula: C₁₂H₁₂N₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C12H12N2O2/c15-7-9-1-3-13-11(5-9)12-6-10(8-16)2-4-14-12/h1-6,15-16H,7-8H2
• InChI key: InChIKey=RRXGRDMHWYLJSY-UHFFFAOYSA-N
• SMILES: OCc1ccnc(-c2cc(CO)ccn2)c1