3-Bromoadamantane-1-carboxylic acid

CAS: 21816-08-0

Ref. 3D-FB10494

Product Information

• Name: 3-Bromoadamantane-1-carboxylic acid
• Synonyms: (5R,7R)-3-bromotricyclo[3.3.1.1~3,7~]decane-1-carboxylate, 1-Adamantanecarboxylic acid, 3-bromo-, 1-Bromo-3-carboxyadamantane, 1-Bromoadamantane-3-carboxylic acid, 3-Bromo-1-adamantanecarboxylic acid, 3-Bromo-1-carboxyadamantane, 3-Bromoadamantan-1-carboxylic acid, 3-Bromotricyclo[3.3.1.1^3,7]decane-1-carboxylic acid, 3-Bromotricyclo[3.3.1.1~3,7~]Decane-1-Carboxylic Acid, Tricyclo[3.3.1.1^3,7]decane-1-carboxylic acid, 3-bromo-, 3-Bromotricyclo[3.3.1.13,7]decane-1-carboxylic acid, Tricyclo[3.3.1.13,7]decane-1-carboxylic acid, 3-bromo-

Description

3-Bromoadamantane-1-carboxylic acid is a potent inhibitor of sphingosine kinase. It is a synthetic compound that was developed to inhibit the activity of sphingosine kinase and thus reduce the levels of sphingosines in cells. 3-Bromoadamantane-1-carboxylic acid has been shown to be effective against multikinases, including caspases and protein kinases. The drug is also able to inhibit tumor growth in animals. The mechanism by which 3-bromoadamantane-1-carboxylic acid inhibits tumor growth is unknown but may involve its ability to bind to the ATP binding site on the enzyme complex or its ability to form a noncompetitive inhibitor with ATP.

• Brand: Biosynth

Chemical properties

• Molecular weight: 259.14 g/mol
• Formula: C₁₁H₁₅BrO₂
• Purity: Min. 95%
• Color/Form: White Off-White Powder