(2-bromo-6-fluorophenyl)boronic Acid
CAS: 913835-80-0
Ref. 3D-FB105575
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued | ||
| 100g | Discontinued |
Product Information
- 2-Bromo-6-fluorophenylboronic acid
- Boronic acid, B-(2-bromo-6-fluorophenyl)-
- Boronic acid, (2-bromo-6-fluorophenyl)-
- B-(2-Bromo-6-fluorophenyl)boronic acid
2-Bromo-6-fluorophenylboronic acid is a boronic acid that can be used for the synthesis of boronate esters. It is a trimethylated compound that can be prepared by the reaction of potassium t-butoxide and 2-bromo-6-fluorobenzeneboronic acid in the presence of lithium diisopropylamide. The synthesis proceeds at low temperatures in the presence of lithium chloride, resulting in an increase in yield. A salt formation process is also involved, which may be necessary to form a stable product. This is typically done by adding a base such as sodium carbonate or potassium carbonate. The diisopropylamide facilitates this reaction by acting as a base catalyst.br>br>
The synthesis begins with the treatment of 2-bromo-6-fluorobenzeneboronic acid with potassium t-butoxide in an inert solvent. This produces trim
