5-Bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

Ref. 3D-FB10581

Product Information

• Name: 5-Bromo-2-chloro-3-nitropyridine
• Brand: Biosynth
• Description: 5-Bromo-2-chloro-3-nitropyridine is a chemical compound that has been shown to have anticancer activity. It has been found to inhibit the phosphoinositide 3 kinase (PI3K) and the mammalian target of rapamycin complex 1 (mTORC1). This drug is also a potent inhibitor of the kinase shp2, which regulates cell proliferation and apoptosis. 5-Bromo-2-chloro-3-nitropyridine inhibits tumor growth in vitro and in vivo. The mechanism of this inhibition may be due to 5-bromo-2,3 nitropyridine's ability to inhibit inflammatory genes such as NFκβ, IL1β, and IL6. 5 – Bromo - 2 - chloro - 3 - nitropyridine has also been shown to inhibit death pathways in cells by inhibiting proapoptotic protein Bax.

Chemical properties

• Molecular weight: 237.44 g/mol
• Formula: C₅H₂BrClN₂O₂
• Purity: Min. 95%
• Color/Form: Powder