4-Bromoisoxazole
CAS:
Ref. 3D-FB10885
Product Information
4-Bromoisoxazole is a reactive isoxazole that can be prepared by the reaction of an azide and a boronic ester. This compound has been shown to be effective for the treatment of cancer, but it also has an inhibitory effect on the synthesis of proteins and enzymes. The 4-bromoisoxazole can be synthesized from phenyl substituted isoxazoles and palladium-catalyzed cross-coupling reactions. Preparative methods for this compound include the use of acetonitrile as solvent with a dipolarity of 0.5D or greater, and argon as inert gas at atmospheric pressure. Hydrochloric acid should not be used in these preparations as it will react with 4-bromoisoxazole to produce toxic hydrochloric acid fumes.
Chemical properties
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