Bz-Val-Gly-Arg-AMC trifluoroacetate salt

CAS: 87779-49-5

Ref. 3D-FB110482

Product Information

• Name: Bz-Val-Gly-Arg-AMC trifluoroacetate salt
• Brand: Biosynth
• Description: Bz-Val-Gly-Arg-AMC is a growth factor that activates the extracellular signal-regulated protein kinase (ERK) pathway. The activation of this pathway results in an increase in cellular proliferation and inhibition of tumor growth. Bz-Val-Gly-Arg-AMC has been shown to activate ERK by interacting with VSMCs, which are cells that act as a structural component of blood vessels and play a role in regulating blood flow. This compound also induces phosphorylation of glycogen synthase kinase 3β and inhibits its activity, leading to increased protein synthesis through glycolysis. Bz-Val-Gly-Arg-AMC can be used as an inhibitor to bortezomib, a proteolytic enzyme that is used to treat cancer.

Chemical properties

• Molecular weight: 591.66 g/mol
• Formula: C₃₀H₃₇N₇O₆
• Purity: Min. 95%