N-Boc-(R)-Nipecotic acid

CAS: 163438-09-3

Ref. 3D-FB11141

Product Information

• Name: N-Boc-(R)-Nipecotic acid
• Synonyms: (3R)-1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid, (3R)-1-(tert-butoxycarbonyl)piperidine-3-carboxylate, (3R)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid, (3R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid, (3R)-1-[(tert-Butoxy)carbonyl]piperidine-3-carboxylic acid, (3R)-1-[[(1,1-Dimethylethyl)oxy]carbonyl]-3-piperidinecarboxylic acid, (3R)-Piperidine-1,3-dicarboxylic acid 1-tert-butyl ester, (R)-(-)-N-Boc-nipecotic acid, (R)-1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid, (R)-1-Boc-nipecotic acid, (R)-Boc-Nip-OH, (R)-Boc-Nipecotic acid, (R)-N-(tert-Butoxycarbonyl)nipecotic acid, (R)-N-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid, 1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (3R)-, 1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (R)-, 1-(1,1-Dimethylethyl) (3R)-1,3-piperidinedicarboxylate, 1-(Tert-Butoxycarbonyl)Piperidine-3-Carboxylic Acid, 1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid, 3-R-(-)-BOC-piperidinecarboxylic acid, Boc (R)-nipecotic acid, N-tert-Butoxycarbonyl-(R)-nipecotic acid

Description

N-Boc-(R)-Nipecotic acid is a synthetic compound that is used in the treatment of lymphocytic leukemia, chronic lymphocytic leukemia, and other types of cancer. It is a dry powder that can be taken orally or subcutaneously. N-Boc-(R)-Nipecotic acid binds to p53 mutations and inhibits DNA synthesis. This drug has been shown to reduce the size of tumors in mice with subcutaneous tumors and has been found to be effective against leukemia cells in vitro. The development of this drug was rationalized on the basis of fluorescence profiles.

• Brand: Biosynth

Chemical properties

• Molecular weight: 229.27 g/mol
• Formula: C₁₁H₁₉NO₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-6-4-5-8(7-12)9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m1/s1
• InChI key: InChIKey=NXILIHONWRXHFA-MRVPVSSYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)O)C1