3-(1H-1,2,3-Benzotriazol-1-yl)butanoic acid

Ref. 3D-FB116613

Product Information

• Name: 3-(1H-1,2,3-Benzotriazol-1-yl)butanoic acid
• Brand: Biosynth
• Description: 3-(1H-1,2,3-Benzotriazol-1-yl)butanoic acid (BTB) is a benzotriazole derivative and a potential drug that has been modified to be more potent and selective. BTB is designed to inhibit the activity of bacterial enzymes, such as dehydrocholic acid synthase (DHCS), which are involved in bile acid synthesis. BTB binds to the active site of DHCS and blocks its activity. This inhibition prevents the formation of DHCS substrates and leads to the accumulation of dehydrocholic acid, an intermediate in bile acid synthesis. BTB also inhibits other enzymes involved in bile acid synthesis, such as 3α-hydroxysteroid dehydrogenase and 3β-hydroxysteroid dehydrogenase.

Chemical properties

• Molecular weight: 205.21 g/mol
• Formula: C₁₀H₁₁N₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H11N3O2/c1-7(6-10(14)15)13-9-5-3-2-4-8(9)11-12-13/h2-5,7H,6H2,1H3,(H,14,15)
• InChI key: InChIKey=FEKISXNJRGSDHP-UHFFFAOYSA-N
• SMILES: CC(CC(=O)O)n1nnc2ccccc21