6-Bromo-4-methylquinolin-2(1H)-one

CAS: 89446-19-5

Ref. 3D-FB132894

Product Information

• Name: 6-Bromo-4-methylquinolin-2(1H)-one
• Synonyms: 2(1H)-quinolinone, 6-bromo-4-methyl-, 2(1H)-quinolinone, 6-bromo-4-methyl-, 2-Quinolinol, 6-Bromo-4-Methyl-, 6-bromo-4-methylquinolin-2(1H)-one

Description

6-Bromo-4-methylquinolin-2(1H)-one is a quinoline with an electron-donating group (bromoaniline) and an electron-withdrawing group. It has been used as a starting material for the synthesis of new quinolines. The steric effect of the bromoaniline group on the 6-position of 6-bromo-4-methylquinolin-2(1H)-one is thought to be responsible for its high reactivity in condensation reactions. The optimized synthetic procedure for 6-bromo-4-methylquinolin-2(1H)-one involves heating crotonate in the presence of bromoaniline, which leads to a rapid reaction that can be monitored by thin layer chromatography (TLC).
6 -Bromo -4 -methylquinolin -2 (1 H) -one has been used as a reagent in

• Brand: Biosynth

Chemical properties

• Molecular weight: 238.08 g/mol
• Formula: C₁₀H₈BrNO
• Purity: Min. 95%
• InChI: InChI=1S/C10H8BrNO/c1-6-4-10(13)12-9-3-2-7(11)5-8(6)9/h2-5H,1H3,(H,12,13)
• InChI key: InChIKey=NOQMJGOVUYZKIA-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)[nH]c2ccc(Br)cc12