2-(3-Bromophenyl)ethanamine

CAS: 58971-11-2

Ref. 3D-FB140168

Product Information

• Name: 2-(3-Bromophenyl)ethanamine
• Synonyms: 2-(3-Bromophenyl)Ethanaminium, 2-(3-Bromophenyl)Ethanamine, 3-Bromo-benzeneethanamine

Description

2-(3-Bromophenyl)ethanamine is an affinity ligand for the 5-hydroxytryptamine receptor 7 (5-HT7). It has a high affinity for the 5-HT7 receptor and can also be used to study other serotonin receptors. This compound has been shown to bind to the 5-HT7 with a Kd of 0.3 nM and no significant binding at other serotonin receptors. It was found that 2-(3-bromophenyl)ethanamine does not inhibit the uptake of serotonin from synaptosomal preparations, but does inhibit the uptake of serotonin from cerebrospinal fluid. These results were confirmed in vitro using radioligand binding assays and autoradiography, demonstrating that 2-(3-bromophenyl)ethanamine binds selectively to the 5-HT7 receptor.

• Brand: Biosynth

Chemical properties

• Molecular weight: 200.08 g/mol
• Formula: C₈H₁₀BrN
• Purity: Min. 95%
• Color/Form: Colorless Powder
• InChI: InChI=1S/C8H10BrN/c9-8-3-1-2-7(6-8)4-5-10/h1-3,6H,4-5,10H2
• InChI key: InChIKey=ORHRHMLEFQBHND-UHFFFAOYSA-N
• SMILES: NCCc1cccc(Br)c1