6-Bromo-pyrazolo[1,5-a]pyrimidine

CAS: 705263-10-1

Ref. 3D-FB140359

Product Information

• Name: 6-Bromo-pyrazolo[1,5-a]pyrimidine
• Brand: Biosynth
• Description: 6-Bromo-pyrazolo[1,5-a]pyrimidine is a bone morphogenetic protein (BMP) inhibitor. It has been shown to be a potent inhibitor of the tyrosine kinase activity of BMP receptors and may be useful for the development of new strategies for the treatment of osteoporosis. 6-Bromo-pyrazolo[1,5-a]pyrimidine is also an effective inhibitor of the proliferation and survival of cancer cells. It inhibits cell growth by interfering with cellular signaling pathways that regulate these processes. 6-Bromo-pyrazolo[1,5-a]pyrimidine was also found to inhibit the production of bone morphogenetic protein 2 (BMP2) in mouse calvaria cells without affecting other bone metabolism markers such as alkaline phosphatase or osteocalcin.

Chemical properties

• Molecular weight: 198.02 g/mol
• Formula: C₆H₄BrN₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H4BrN3/c7-5-3-8-6-1-2-9-10(6)4-5/h1-4H
• InChI key: InChIKey=VDHTXLUCUNPVLO-UHFFFAOYSA-N
• SMILES: Brc1cnc2ccnn2c1