5-Bromo-2-(hydroxymethyl)phenol

CAS: 170434-11-4

Ref. 3D-FB140725

Product Information

• Name: 5-Bromo-2-(hydroxymethyl)phenol
• Synonyms: Benzenemethanol, 4-Bromo-2-Hydroxy-

Description

5-Bromo-2-(hydroxymethyl)phenol (5-BHP) is a synthetic small molecule that activates the death receptor CD95. It has been shown to induce tumor regression in experimental models of cancer. 5-BHP can be used as a cancer therapeutic or for the treatment of inflammatory conditions such as rheumatoid arthritis and psoriasis. 5-BHP binds to the death protein pd-l1, which initiates downstream signaling pathways that lead to activation of caspases and apoptosis. This agent also interacts with programmed death ligand 1 (PD-L1), which is expressed on activated T cells and may be involved in antitumor responses. These interactions are being investigated for their potential use in drug development, including optimization and biochemical techniques to characterize the binding affinity of 5-BHP with PD-L1.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.03 g/mol
• Formula: C₇H₇BrO₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H7BrO2/c8-6-2-1-5(4-9)7(10)3-6/h1-3,9-10H,4H2
• InChI key: InChIKey=CHVJSQNPFPRTPB-UHFFFAOYSA-N
• SMILES: OCc1ccc(Br)cc1O