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Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol
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Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol

CAS: 47623-98-3

Ref. 3D-FB148191

10mg
166.00 €
25mg
287.00 €
50mg
406.00 €
100mg
580.00 €
250mg
1,018.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol
Synonyms:
  • 4,6(1H,5H)-Pyrimidinedione, 5-(3-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene)-1,3-diethyldihydro-2-thioxo-
  • 4,6(1H,5H)-Pyrimidinedione, 5-[3-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-
  • 5,5'-prop-1-en-1-yl-3-ylidenebis(1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione)
  • 5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
  • 5-[3-(1,3-diethyl-6-hydroxy-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)prop-2-en-1-ylidene]-1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
  • Bis(1,3-diethylthiobarbiturate)trimethineoxonol
  • Bis(1,3-diethylthiobarbituric acid)trimethine oxonol
  • DiSBAC<sub>2</sub>(3)
Description:

Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol (BTTMO) is a compound class of drugs that inhibit the ATP-binding cassette transporter and block the transport of cellular metabolites across the mitochondrial membrane. This inhibition leads to a decrease in cellular ATP levels and an increase in cytosolic calcium. BTTMO has shown promising results in animal models for treatment of cervical cancer, which may be due to its ability to stimulate epidermal growth factor receptor signaling. BTTMO also inhibits energy metabolism by inhibiting mitochondrial membrane potential and blocking atp-sensitive potassium channels. It also induces gamma-aminobutyric acid release from neurons, leading to hyperpolarization of the cell membrane.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
436.55 g/mol
Formula:
C19H24N4O4S2
Purity:
Min. 95%
Color/Form:
Dark Purple Solid
InChI:
InChI=1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+
InChI key:
InChIKey=VJYNRXFXHKIGLT-MDZDMXLPSA-N
SMILES:
CCN1C(=O)C(=C/C=C/C2C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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