Product Information
Name:BOP-Cl
Synonyms:
- Bis(2-oxo-3-oxazolidinyl)phosphinic chloridePhosphoric acid bis(2-oxooxazolidide) chloride
Brand:Biosynth
Description:BOP-Cl is a phosphoric acid derivative used as a coupling reagent for amide and ester formation. BOP-Cl is effective in the acylation of N-methylated amino acids and in the introduction of thiopeptide bonds on imino acids. BOP-Cl requires mild conditions, gives good yields and suppresses epimerisation. BOP-Cl and other phosphinic acids activate the carboxylic acid by forming a carboxylic-phosphinic mixed anhydride, in which stereochemistry is conveniently retained. BOP-Cl gives good performances in the acylation of N-methylated amino acids due to intramolecular base catalysis.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:254.56 g/mol
Formula:C6H8ClN2O5P
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C6H8ClN2O5P/c7-15(12,8-1-3-13-5(8)10)9-2-4-14-6(9)11/h1-4H2
InChI key:InChIKey=KLDLRDSRCMJKGM-UHFFFAOYSA-N
SMILES:O=C1OCCN1P(=O)(Cl)N1CCOC1=O
Technical inquiry about: BOP-Cl
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