1-tert-butyl-4,4-Diphenyl-piperidine

CAS: 57982-78-2

Ref. 3D-FB156517

Product Information

• Name: 1-tert-butyl-4,4-Diphenyl-piperidine
• Synonyms: Budipine
• Brand: Biosynth
• Description: 1-tert-butyl-4,4-Diphenyl-piperidine is a drug that binds to the dopamine D2 receptor. It inhibits locomotor activity in animals and has been shown to be neurotoxic in vivo. 1-tert-butyl-4,4-Diphenyl-piperidine has been shown to exhibit antioxidative properties, which may be due to its ability to scavenge reactive oxygen species (ROS) or inhibit lipid peroxidation. This drug also has antimuscarinic effects and is used as an antiparkinsonian agent. It is a competitive antagonist at the muscarinic M1 receptor and displays high affinity for the dopamine D2 receptor in vitro. Moreover, it increases striatal dopamine concentrations in vivo and exhibits antiparkinsonian effects when administered intraperitoneally to rats. Fatty acid metabolism is inhibited by this drug, which may lead to an increase in endogenous substances such as gamma-aminob

Chemical properties

• Molecular weight: 293.45 g/mol
• Formula: C₂₁H₂₇N
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C21H27N/c1-20(2,3)22-16-14-21(15-17-22,18-10-6-4-7-11-18)19-12-8-5-9-13-19/h4-13H,14-17H2,1-3H3
• InChI key: InChIKey=QIHLUZAFSSMXHQ-UHFFFAOYSA-N
• SMILES: CC(C)(C)N1CCC(c2ccccc2)(c2ccccc2)CC1